GTF2H1

Across TCGA pan-cancer cohorts, GTF2H1 Mutation is linked to patient survival in 2 of 34 cancer types, making it a survival-associated GTF2H1 data layer compared with 20 for mass-spec protein and 5 for mass-spec protein.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher GTF2H1 Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated GTF2H1 expression acts as an unfavorable survival marker.

COAD and ESCA are the cancer types where GTF2H1 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Median	III,IV	0.019	0.698	<.001	11	view →
ESCA	OS	Median	II,III,IV	0.321	0.685	.035	6	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

GTF2H1–COAD (DFS)

Open the COAD breakdown →