GTF2H1

Across TCGA pan-cancer cohorts, GTF2H1 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated GTF2H1 data layer compared with 20 for mass-spec protein and 2 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher GTF2H1 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated GTF2H1 expression acts as an unfavorable survival marker, although some lineages such as LUAD and OV show a favorable association.

LUAD, CCRCC, and COAD are the cancer types where GTF2H1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	DFS	Median	III,IV	0.995	0.485	.003	22	view →
CCRCC	DFS	Median	III,IV	0.388	0.713	.006	19	view →
COAD	DFS	Tertile	All	0.916	1.000	.029	12	view →
OV	DFS	Median	All	0.919	0.549	.036	8	view →
PDAC	DFS	Median	All	0.474	0.339	.030	4	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

GTF2H1–LUAD (DFS)

Open the LUAD breakdown →