GTF2H1

Across TCGA patient cohorts, GTF2H1 RNA expression is significantly associated with the mutation status of many other genes, with 10,760 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GTF2H1-associated genes across cancer lineages are TP53, TTN, and MRC1. Each is linked with GTF2H1 in more than 5 cancer types. Because this analysis shows association rather than direction, both GTF2H1-to-partner and partner-to-GTF2H1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TP53 grouped by GTF2H1-low versus GTF2H1-high in SKCM.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GTF2H1→partner) and Y-score (partner→GTF2H1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	TP53 →	+1.623	+0.397	<.001	.001	3	6
STAD	TTN →	+0.974	+0.174	<.001	<.001	3	5
LUSC	MRC1 →	+2.169	+0.296	<.001	.001	3	4
UCEC	CDH6 →	+4.643	+0.563	<.001	<.001	3	4
UCEC	FREM2 →	+1.527	+0.325	<.001	<.001	3	4
UCEC	COL6A6 →	+2.169	+0.394	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,760 associations by consensus.

TP53 by GTF2H1 expression — SKCM

Explore this box plot interactively →