GTF2H1

Across TCGA cell cohorts, GTF2H1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,041 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible GTF2H1-associated GO terms across cancer lineages are Protein histidyl modification to diphthamide, Peptidyl-histidine modification, and Transcription by RNA polymerase I. Each is linked with GTF2H1 in more than 12 cancer types. Because this analysis shows association rather than direction, both GTF2H1-to-partner and partner-to-GTF2H1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein histidyl modification to diphthamide grouped by GTF2H1-low versus GTF2H1-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GTF2H1→partner) and Y-score (partner→GTF2H1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Protein histidyl modification to diphthamide →	+0.121	+1.172	<.001	<.001	3	13
OESOPHAGUS	Peptidyl-histidine modification →	+0.121	+1.172	<.001	<.001	3	13
LARGE_INTESTINE	Transcription by RNA polymerase I →	+0.112	+0.687	<.001	<.001	3	12
OVARY	Phosphatidylinositol dephosphorylation →	+0.053	+0.598	.002	.001	3	12
LUNG_NSCLC_LUSC	Telomere tethering at nuclear periphery →	+0.109	+0.863	.004	.006	3	12
PANCREAS	Positive regulation of mRNA processing →	+0.092	+0.625	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,041 associations by consensus.

Protein histidyl modification to diphthamide by GTF2H1 expression — OESOPHAGUS

Explore this box plot interactively →