GTF2H1

Across TCGA cell cohorts, GTF2H1 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible GTF2H1-associated genes across cancer lineages are TMSB4Y and GSG1L2. Each is linked with GTF2H1 in more than 1 cancer types. Because this analysis shows association rather than direction, both GTF2H1-to-partner and partner-to-GTF2H1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TMSB4Y grouped by GTF2H1-low versus GTF2H1-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GTF2H1→partner) and Y-score (partner→GTF2H1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	TMSB4Y →	+1.183	+3.556	.001	.007	3	1
LARGE_INTESTINE	GSG1L2 →	+0.011	+3.700	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

TMSB4Y by GTF2H1 expression — LARGE_INTESTINE

Explore this box plot interactively →