GTF2F2P1

Across TCGA pan-cancer cohorts, GTF2F2P1 RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated GTF2F2P1 data layer.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher GTF2F2P1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated GTF2F2P1 expression acts as an unfavorable survival marker, although some lineages such as UCEC and ESCA show a favorable association.

HNSC, ACC, and KIRP are the cancer types where GTF2F2P1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	OS	Tertile	III,IV	0.207	0.434	.001	84	view →
ACC	OS	Median	All	0.229	0.828	<.001	82	view →
KIRP	DFS	Quartile	All	0.763	0.915	.001	67	view →
MESO	OS	Median	All	0.431	0.665	<.001	40	view →
KICH	OS	Quartile	II,III,IV	0.510	0.947	.002	39	view →
LUAD	DFS	Quartile	IV	0.370	0.774	.016	21	view →
STAD	OS	Tertile	All	0.625	0.825	.024	18	view →
LIHC	OS	Median	III,IV	0.338	0.624	.009	18	view →
LUSC	DFS	Median	III,IV	0.493	0.925	.030	18	view →
KIRC	DFS	Quartile	IV	0.276	0.540	.012	16	view →
UVM	DFS	Tertile	III,IV	0.129	0.673	.017	15	view →
UCEC	DFS	Median	III,IV	0.857	0.728	.013	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

GTF2F2P1–HNSC (OS)

Open the HNSC breakdown →