Across TCGA patient cohorts, GTF2F2 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,242 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible GTF2F2-associated proteins across cancer lineages are TPT1, GTF2F1, and KPNA3. Each is linked with GTF2F2 in more than 6 cancer types. Because this analysis shows association rather than direction, both GTF2F2-to-partner and partner-to-GTF2F2 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GTF2F2→partner) and Y-score (partner→GTF2F2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	TPT1 →	+0.364	+0.229	<.001	<.001	3	7
GBM	GTF2F1 →	+0.418	+0.489	<.001	<.001	3	7
COAD	KPNA3 →	+0.364	+0.631	<.001	<.001	3	7
COAD	SUGT1 →	+0.305	+0.486	<.001	<.001	3	6
LSCC	CUL4A →	+0.479	+0.758	<.001	<.001	3	6
OV	GPALPP1 →	+0.377	+0.583	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,242 associations by consensus.

Exploration

GTF2F2 survival (RNA) · tumor vs normal (RNA) · all GTF2F2 data types