Across TCGA patient cohorts, GTF2F2 protein abundance is significantly associated with the RNA expression of many other genes, with 16,348 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible GTF2F2-associated genes across cancer lineages are RFC3, POLR1D, and SLC25A15. Each is linked with GTF2F2 in more than 7 cancer types. Because this analysis shows association rather than direction, both GTF2F2-to-partner and partner-to-GTF2F2 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GTF2F2→partner) and Y-score (partner→GTF2F2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	RFC3 →	+0.885	+0.325	<.001	<.001	3	8
HNSC	POLR1D →	+0.434	+0.254	<.001	<.001	3	8
LSCC	SLC25A15 →	+0.705	+0.275	<.001	<.001	3	7
BRCA	EXOSC8 →	+0.555	+0.261	<.001	<.001	2	8
LSCC	CKAP2 →	+0.933	+0.325	<.001	<.001	3	7
OV	IPO5 →	+0.675	+0.409	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,348 associations by consensus.

Exploration

GTF2F2 survival (RNA) · tumor vs normal (RNA) · all GTF2F2 data types