Across TCGA patient cohorts, GTF2F2 mutation is significantly associated with the RNA expression of many other genes, with 107 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GTF2F2-associated genes across cancer lineages are RN7SKP60, SLC25A31, and SLC45A2. Each is linked with GTF2F2 in more than 1 cancer types. Because this analysis shows association rather than direction, both GTF2F2-to-partner and partner-to-GTF2F2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GTF2F2→partner) and Y-score (partner→GTF2F2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RN7SKP60 →	+0.317	+3.350	<.001	.001	3	2
UCEC	SLC25A31 →	+0.130	+2.953	.003	.007	3	1
UCEC	SLC45A2 →	+0.373	+3.277	<.001	.008	3	1
UCEC	BMT2 →	+0.768	+3.202	<.001	.009	3	1
UCEC	HDGFL3 →	+0.942	+3.202	.004	.009	3	1
UCEC	MYOZ2 →	+0.356	+3.536	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 107 associations by consensus.

Exploration

GTF2F2 survival (RNA) · tumor vs normal (RNA) · all GTF2F2 data types