GTF2F1

Across TCGA patient cohorts, GTF2F1 protein abundance is significantly associated with the RNA expression of many other genes, with 16,171 significant associations in total. GBM shows the largest number of these associations.

The most reproducible GTF2F1-associated genes across cancer lineages are POLR1D, NUFIP1, and CMAHP. Each is linked with GTF2F1 in more than 6 cancer types. Because this analysis shows association rather than direction, both GTF2F1-to-partner and partner-to-GTF2F1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GTF2F1 versus POLR1D in BRCA, with a Pearson correlation of 0.36.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GTF2F1→partner) and Y-score (partner→GTF2F1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	POLR1D →	+0.451	+0.300	<.001	<.001	3	7
LSCC	NUFIP1 →	+0.605	+0.352	<.001	<.001	3	7
OV	CMAHP →	-0.877	-0.245	<.001	<.001	3	7
LSCC	SLC25A15 →	+0.635	+0.293	<.001	<.001	3	6
LSCC	KPNA3 →	+0.608	+0.285	<.001	<.001	3	6
GBM	EXOSC8 →	+0.568	+0.416	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,171 associations by consensus.

GTF2F1 vs POLR1D — BRCA

Explore this scatter interactively →