Across TCGA patient cohorts, GTF2E2 protein abundance is significantly associated with the protein abundance of many other proteins, with 26,479 significant associations in total. GBM shows the largest number of these associations.

The most reproducible GTF2E2-associated proteins across cancer lineages are BCLAF1, CDC5L, and COIL_T303. Each is linked with GTF2E2 in more than 9 cancer types. Because this analysis shows association rather than direction, both GTF2E2-to-partner and partner-to-GTF2E2 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GTF2E2→partner) and Y-score (partner→GTF2E2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	BCLAF1 →	+0.296	+0.237	<.001	<.001	3	10
GBM	CDC5L →	+0.251	+0.191	<.001	<.001	3	10
LSCC	COIL_T303 →	+1.345	+0.410	<.001	<.001	3	10
OV	DDX5 →	+0.372	+0.308	<.001	.002	3	10
GBM	SF3B2 →	+0.260	+0.234	<.001	<.001	3	10
LSCC	SNW1 →	+0.282	+0.361	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 26,479 associations by consensus.

Exploration

GTF2E2 survival (RNA) · tumor vs normal (RNA) · all GTF2E2 data types