Across TCGA patient cohorts, GTF2E2 mutation is significantly associated with the RNA expression of many other genes, with 2,911 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GTF2E2-associated genes across cancer lineages are MIR548N, SERPINB8P1, and H2BC1. Each is linked with GTF2E2 in more than 1 cancer types. Because this analysis shows association rather than direction, both GTF2E2-to-partner and partner-to-GTF2E2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GTF2E2→partner) and Y-score (partner→GTF2E2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	MIR548N →	+0.700	+4.199	<.001	.004	3	2
UCEC	SERPINB8P1 →	+0.088	+2.464	<.001	.007	3	2
SKCM	H2BC1 →	+0.073	+4.884	.006	.004	3	2
BRCA	MIR4456 →	+0.602	+8.055	<.001	.007	3	1
BLCA	DUXAP6 →	+0.141	+5.251	.002	.006	3	1
UCEC	HSPE1-MOB4 →	+0.144	+1.962	.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,911 associations by consensus.

Exploration

GTF2E2 survival (RNA) · tumor vs normal (RNA) · all GTF2E2 data types