GTF2E1

Across TCGA patient cohorts, GTF2E1 protein abundance is significantly associated with the RNA expression of many other genes, with 10,645 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible GTF2E1-associated genes across cancer lineages are ALYREF, GTF2E2, and RAD51AP1. Each is linked with GTF2E1 in more than 6 cancer types. Because this analysis shows association rather than direction, both GTF2E1-to-partner and partner-to-GTF2E1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GTF2E1 versus ALYREF in UCEC, with a Pearson correlation of 0.36.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GTF2E1→partner) and Y-score (partner→GTF2E1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ALYREF →	+1.151	+0.219	.001	<.001	3	7
HNSC	GTF2E2 →	+0.954	+0.274	.006	.001	3	7
BRCA	RAD51AP1 →	+0.973	+0.305	<.001	<.001	3	6
LUAD	ECT2 →	+0.861	+0.172	<.001	<.001	3	6
BRCA	CENPA →	+1.232	+0.330	<.001	<.001	3	6
LUAD	KIF14 →	+1.196	+0.168	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,645 associations by consensus.

GTF2E1 vs ALYREF — UCEC

Explore this scatter interactively →