GTF2E1

Across TCGA cell cohorts, GTF2E1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,268 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible GTF2E1-associated GO terms across cancer lineages are Protein localization to chromosome, Nucleocytoplasmic transport, and Double-strand break repair via alternative nonhomologous end joining. Each is linked with GTF2E1 in more than 15 cancer types. Because this analysis shows association rather than direction, both GTF2E1-to-partner and partner-to-GTF2E1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein localization to chromosome grouped by GTF2E1-low versus GTF2E1-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GTF2E1→partner) and Y-score (partner→GTF2E1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Protein localization to chromosome →	+0.090	+0.607	.002	.002	3	16
BLOOD_Lymphoma	Nucleocytoplasmic transport →	+0.077	+0.836	<.001	<.001	3	14
OVARY	Double-strand break repair via alternative nonhomologous end joining →	+0.110	+0.520	<.001	<.001	3	14
BONE	Double-strand break repair via nonhomologous end joining →	+0.061	+0.646	<.001	<.001	3	14
OESOPHAGUS	RNA polymerase II preinitiation complex assembly →	+0.091	+0.667	.004	.007	3	14
BLOOD_Lymphoma	Nuclear transport →	+0.077	+0.832	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,268 associations by consensus.

Protein localization to chromosome by GTF2E1 expression — PANCREAS

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