GTF2A2

Across TCGA patient cohorts, GTF2A2 protein abundance is significantly associated with the RNA expression of many other genes, with 11,267 significant associations in total. GBM shows the largest number of these associations.

The most reproducible GTF2A2-associated genes across cancer lineages are GTF2A1, LIN52, and VNN2. Each is linked with GTF2A2 in more than 6 cancer types. Because this analysis shows association rather than direction, both GTF2A2-to-partner and partner-to-GTF2A2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GTF2A2 versus GTF2A1 in HNSC, with a Pearson correlation of 0.27.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GTF2A2→partner) and Y-score (partner→GTF2A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	GTF2A1 →	+0.517	+0.225	.002	<.001	3	7
HNSC	LIN52 →	+0.485	+0.296	<.001	<.001	3	6
HNSC	VNN2 →	-0.947	-0.244	<.001	<.001	3	6
LSCC	FANCM →	+0.581	+0.395	<.001	<.001	3	5
LSCC	TAF5 →	+0.487	+0.271	<.001	<.001	3	5
LSCC	ARHGAP19 →	+0.464	+0.226	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,267 associations by consensus.

GTF2A2 vs GTF2A1 — HNSC

Explore this scatter interactively →