GTF2A1

Across TCGA patient cohorts, GTF2A1 protein abundance is significantly associated with the RNA expression of many other genes, with 9,525 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible GTF2A1-associated genes across cancer lineages are FKBP3, ERG28, and DNAAF2. Each is linked with GTF2A1 in more than 5 cancer types. Because this analysis shows association rather than direction, both GTF2A1-to-partner and partner-to-GTF2A1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GTF2A1 versus FKBP3 in LUAD, with a Pearson correlation of 0.43.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GTF2A1→partner) and Y-score (partner→GTF2A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	FKBP3 →	+0.616	+0.247	<.001	<.001	3	6
HNSC	ERG28 →	+0.560	+0.192	.006	.006	3	5
HNSC	DNAAF2 →	+0.576	+0.214	<.001	.001	3	5
LSCC	FANCM →	+0.525	+0.238	.001	.002	3	5
HNSC	SNW1 →	+0.673	+0.255	.001	<.001	3	5
BRCA	DICER1 →	+0.923	+0.280	<.001	.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,525 associations by consensus.

GTF2A1 vs FKBP3 — LUAD

Explore this scatter interactively →