GTDC1

Across TCGA patient cohorts, GTDC1 RNA expression is significantly associated with the protein abundance of many other proteins, with 18,464 significant associations in total. GBM shows the largest number of these associations.

The most reproducible GTDC1-associated proteins across cancer lineages are DBN1, DAPK3, and FERMT2. Each is linked with GTDC1 in more than 5 cancer types. Because this analysis shows association rather than direction, both GTDC1-to-partner and partner-to-GTDC1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GTDC1 versus DBN1 in GBM, with a Pearson correlation of 0.61.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GTDC1→partner) and Y-score (partner→GTDC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	DBN1 →	+0.365	+0.408	<.001	<.001	3	6
BRCA	DAPK3 →	+0.330	+0.320	.005	.006	3	5
BRCA	FERMT2 →	+0.551	+0.343	<.001	.004	3	5
BRCA	FLNA →	+0.386	+0.395	.008	<.001	3	5
OV	PALLD →	+0.595	+0.309	<.001	.002	3	5
PDAC	DBN1_S142 →	+1.004	+0.386	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,464 associations by consensus.

GTDC1 vs DBN1 — GBM

Explore this scatter interactively →