GTDC1

Across TCGA patient cohorts, GTDC1 protein abundance is significantly associated with the RNA expression of many other genes, with 5,900 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible GTDC1-associated genes across cancer lineages are GFPT2, POSTN, and ST18. Each is linked with GTDC1 in more than 2 cancer types. Because this analysis shows association rather than direction, both GTDC1-to-partner and partner-to-GTDC1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GTDC1 versus GFPT2 in BRCA, with a Pearson correlation of 0.30.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GTDC1→partner) and Y-score (partner→GTDC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	GFPT2 →	+0.736	+0.298	.002	.009	3	3
HNSC	POSTN →	+2.223	+0.591	.003	.005	3	3
GBM	ST18 →	+0.800	+0.249	.006	.001	3	3
OV	CPSF6 →	-0.780	-1.164	.007	.003	3	2
OV	MAD2L2 →	+0.881	+0.943	.002	<.001	3	2
OV	NFKBIE →	+0.962	+1.082	.008	.007	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,900 associations by consensus.

GTDC1 vs GFPT2 — BRCA

Explore this scatter interactively →