GTDC1

Across TCGA cell cohorts, GTDC1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,262 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible GTDC1-associated GO terms across cancer lineages are Primary alcohol metabolic process, Regulation of G1/S transition of mitotic cell cycle, and Transcription initiation at RNA polymerase II promoter. Each is linked with GTDC1 in more than 8 cancer types. Because this analysis shows association rather than direction, both GTDC1-to-partner and partner-to-GTDC1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Primary alcohol metabolic process grouped by GTDC1-low versus GTDC1-high in LUNG_NSCLC_LUAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GTDC1→partner) and Y-score (partner→GTDC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	Primary alcohol metabolic process →	-0.077	-0.513	.008	.001	3	9
SKIN	Regulation of G1/S transition of mitotic cell cycle →	+0.064	+0.567	<.001	.003	3	9
LARGE_INTESTINE	Transcription initiation at RNA polymerase II promoter →	+0.048	+0.546	<.001	<.001	3	9
LARGE_INTESTINE	Endosomal transport →	+0.046	+0.547	<.001	.001	3	8
KIDNEY	Positive regulation of lamellipodium assembly →	+0.128	+0.949	.003	.008	3	8
SOFT_TISSUE	Mitochondrial electron transport, cytochrome c to oxygen →	+0.064	+0.929	.004	.002	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,262 associations by consensus.

Primary alcohol metabolic process by GTDC1 expression — LUNG_NSCLC_LUAD

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