GSX2

Across TCGA patient cohorts, GSX2 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,993 significant associations in total. STAD shows the largest number of these associations.

The most reproducible GSX2-associated GO terms across cancer lineages are Regulation of protein localization to nucleus, Regulation of protein serine/threonine kinase activity, and Maintenance of cell number. Each is linked with GSX2 in more than 11 cancer types. Because this analysis shows association rather than direction, both GSX2-to-partner and partner-to-GSX2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of protein localization to nucleus grouped by GSX2-low versus GSX2-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GSX2→partner) and Y-score (partner→GSX2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Regulation of protein localization to nucleus →	+0.066	+0.065	<.001	<.001	3	12
STAD	Regulation of protein serine/threonine kinase activity →	+0.049	+0.063	<.001	<.001	3	12
STAD	Maintenance of cell number →	+0.054	+0.062	<.001	<.001	3	12
STAD	Positive regulation of amide metabolic process →	+0.062	+0.065	<.001	<.001	3	12
STAD	Signal transduction in response to DNA damage →	+0.049	+0.048	<.001	<.001	3	12
STAD	Fibroblast proliferation →	+0.056	+0.065	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,993 associations by consensus.

Regulation of protein localization to nucleus by GSX2 expression — STAD

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