GSX2

Across TCGA cell cohorts, GSX2 RNA expression is significantly associated with the go_rna of many other GO terms, with 381 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible GSX2-associated GO terms across cancer lineages are Lipoprotein biosynthetic process, Positive regulation of plasma membrane bounded cell projection assembly, and Protein depolymerization. Each is linked with GSX2 in more than 4 cancer types. Because this analysis shows association rather than direction, both GSX2-to-partner and partner-to-GSX2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Lipoprotein biosynthetic process grouped by GSX2-low versus GSX2-high in KIDNEY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GSX2→partner) and Y-score (partner→GSX2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIDNEY	Lipoprotein biosynthetic process →	+0.086	+0.070	.003	.007	2	5
LUNG_NSCLC_LUAD	Positive regulation of plasma membrane bounded cell projection assembly →	+0.029	+0.075	.005	.001	3	3
KIDNEY	Protein depolymerization →	+0.088	+0.111	<.001	.002	3	3
BLOOD_Lymphoma	Regulation of establishment of cell polarity →	+0.064	+0.850	.001	.006	3	3
OVARY	Protein myristoylation →	+0.108	+0.122	<.001	.008	2	4
UPPER_AERODIGESTIVE_TRACT	Regulation of actin filament organization →	+0.052	+0.050	<.001	.004	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 381 associations by consensus.

Lipoprotein biosynthetic process by GSX2 expression — KIDNEY

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