GSX1

Across TCGA patient cohorts, GSX1 protein abundance is significantly associated with the RNA expression of many other genes, with 4,412 significant associations in total. GBM shows the largest number of these associations.

The most reproducible GSX1-associated genes across cancer lineages are YPEL1, SNRPD3, and GGT1. Each is linked with GSX1 in more than 1 cancer types. Because this analysis shows association rather than direction, both GSX1-to-partner and partner-to-GSX1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GSX1 versus YPEL1 in GBM, with a Pearson correlation of 0.28.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GSX1→partner) and Y-score (partner→GSX1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	YPEL1 →	+0.506	+0.810	.002	<.001	3	1
GBM	SNRPD3 →	+0.481	+0.841	<.001	<.001	3	1
GBM	GGT1 →	+0.178	+0.679	<.001	.005	3	1
GBM	CYTH4 →	-0.982	-1.196	<.001	<.001	3	1
GBM	CRYBB2P1 →	+0.451	+0.949	.008	.002	3	1
GBM	SEZ6L →	+2.238	+1.135	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,412 associations by consensus.

GSX1 vs YPEL1 — GBM

Explore this scatter interactively →