GSX1

Across TCGA patient cohorts, GSX1 protein abundance is significantly associated with the protein abundance of many other proteins, with 3,598 significant associations in total. GBM shows the largest number of these associations.

The most reproducible GSX1-associated proteins across cancer lineages are RCOR2_S213, REEP4_S152, and RELB. Each is linked with GSX1 in more than 1 cancer types. Because this analysis shows association rather than direction, both GSX1-to-partner and partner-to-GSX1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GSX1 versus RCOR2_S213 in GBM, with a Pearson correlation of 0.38.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GSX1→partner) and Y-score (partner→GSX1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	RCOR2_S213 →	+0.961	+1.016	<.001	<.001	3	1
GBM	REEP4_S152 →	-0.413	-0.916	.002	<.001	3	1
GBM	RELB →	-0.345	-0.818	<.001	<.001	3	1
GBM	RELL1_S161 →	-0.803	-1.090	<.001	<.001	3	1
GBM	REPS1_S143 →	-0.479	-0.887	<.001	<.001	3	1
GBM	RERE →	+0.491	+1.323	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,598 associations by consensus.

GSX1 vs RCOR2_S213 — GBM

Explore this scatter interactively →