GSTZ1

Across TCGA patient cohorts, GSTZ1 protein abundance is significantly associated with the RNA expression of many other genes, with 12,341 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible GSTZ1-associated genes across cancer lineages are TMEM251, ISCA2, and VTI1B. Each is linked with GSTZ1 in more than 7 cancer types. Because this analysis shows association rather than direction, both GSTZ1-to-partner and partner-to-GSTZ1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GSTZ1 versus TMEM251 in OV, with a Pearson correlation of 0.43.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GSTZ1→partner) and Y-score (partner→GSTZ1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	TMEM251 →	+0.622	+0.582	<.001	<.001	3	7
OV	ISCA2 →	+0.548	+0.500	.003	.002	2	8
HNSC	VTI1B →	+0.479	+0.297	<.001	.001	2	7
BRCA	IFT43 →	+0.515	+0.443	<.001	<.001	3	6
OV	ERG28 →	+0.599	+0.517	<.001	.001	3	6
BRCA	TTC8 →	+1.040	+0.652	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,341 associations by consensus.

GSTZ1 vs TMEM251 — OV

Explore this scatter interactively →