GSTT2B

Across TCGA patient cohorts, GSTT2B mutation is significantly associated with the RNA expression of many other genes, with 35 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GSTT2B-associated genes across cancer lineages are CXorf51B, MIR8054, and RNA5SP414. Each is linked with GSTT2B in more than 1 cancer types. Because this analysis shows association rather than direction, both GSTT2B-to-partner and partner-to-GSTT2B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CXorf51B grouped by GSTT2B-low versus GSTT2B-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GSTT2B→partner) and Y-score (partner→GSTT2B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	CXorf51B →	+0.084	+7.640	<.001	.009	3	2
SKCM	MIR8054 →	+0.618	+7.816	<.001	.008	3	2
UCEC	RNA5SP414 →	+1.792	+4.840	<.001	.003	3	1
UCEC	MIR6515 →	+0.672	+5.335	<.001	.003	3	1
BLCA	RNU6-739P →	+0.298	+7.640	<.001	.009	3	1
BLCA	RNU6-193P →	+0.288	+7.640	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 35 associations by consensus.

CXorf51B by GSTT2B expression — BLCA

Explore this box plot interactively →