GSTT2

Across TCGA patient cohorts, GSTT2 protein abundance is significantly associated with the RNA expression of many other genes, with 3,576 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible GSTT2-associated genes across cancer lineages are PHF12, GABRR2, and TFDP2. Each is linked with GSTT2 in more than 1 cancer types. Because this analysis shows association rather than direction, both GSTT2-to-partner and partner-to-GSTT2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GSTT2 versus PHF12 in HNSC, with a Pearson correlation of 0.32.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GSTT2→partner) and Y-score (partner→GSTT2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	PHF12 →	+0.535	+0.495	.002	.003	3	2
HNSC	GABRR2 →	+1.012	+0.420	<.001	.003	3	2
HNSC	TFDP2 →	+0.667	+0.414	<.001	<.001	3	2
HNSC	ABCC5 →	+1.531	+0.657	.002	<.001	3	2
HNSC	SCLY →	+0.555	+0.428	<.001	.007	3	2
OV	CEP20 →	+0.585	+0.670	.004	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,576 associations by consensus.

GSTT2 vs PHF12 — HNSC

Explore this scatter interactively →