GSTT2

Across TCGA cell cohorts, GSTT2 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,881 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible GSTT2-associated GO terms across cancer lineages are Establishment of Golgi localization, Regulation of extrinsic apoptotic signaling pathway via death domain receptors, and Endosome organization. Each is linked with GSTT2 in more than 7 cancer types. Because this analysis shows association rather than direction, both GSTT2-to-partner and partner-to-GSTT2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Establishment of Golgi localization grouped by GSTT2-low versus GSTT2-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GSTT2→partner) and Y-score (partner→GSTT2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Establishment of Golgi localization →	+0.120	+0.802	.001	<.001	3	8
BONE	Regulation of extrinsic apoptotic signaling pathway via death domain receptors →	+0.156	+0.598	<.001	.006	3	7
SOFT_TISSUE	Endosome organization →	+0.044	+0.637	.001	.006	3	6
CNS	Nucleoside diphosphate metabolic process →	+0.052	+0.679	.004	.002	3	6
OESOPHAGUS	Regulation of intracellular protein transport →	+0.098	+1.502	<.001	.004	3	6
LIVER	Positive regulation of signal transduction by p53 class mediator →	+0.111	+1.043	.001	.004	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,881 associations by consensus.

Establishment of Golgi localization by GSTT2 expression — LIVER

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