GSTP1

Across TCGA patient cohorts, GSTP1 mutation is significantly associated with the RNA expression of many other genes, with 40 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible GSTP1-associated genes across cancer lineages are RNU6-1241P, RN7SKP286, and RN7SL332P. Each is linked with GSTP1 in more than 1 cancer types. Because this analysis shows association rather than direction, both GSTP1-to-partner and partner-to-GSTP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-1241P grouped by GSTP1-low versus GSTP1-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GSTP1→partner) and Y-score (partner→GSTP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	RNU6-1241P →	+0.386	+7.741	<.001	.009	3	2
UCEC	RN7SKP286 →	+0.104	+5.475	<.001	.001	3	2
UCEC	RN7SL332P →	+0.241	+4.716	<.001	<.001	3	2
SKCM	OR8K1 →	+0.039	+5.513	.001	.004	3	1
SKCM	OR5M1 →	+0.752	+6.328	<.001	.001	3	1
SKCM	MIR3131 →	+0.644	+4.979	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 40 associations by consensus.

RNU6-1241P by GSTP1 expression — COAD

Explore this box plot interactively →