GSTP1

Across TCGA cell cohorts, GSTP1 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,444 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible GSTP1-associated GO terms across cancer lineages are Negative regulation of monocyte chemotactic protein-1 production, Negative regulation of smooth muscle cell chemotaxis, and Negative regulation of acute inflammatory response. Each is linked with GSTP1 in more than 11 cancer types. Because this analysis shows association rather than direction, both GSTP1-to-partner and partner-to-GSTP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of monocyte chemotactic protein-1 production grouped by GSTP1-low versus GSTP1-high in BLOOD_Myeloma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GSTP1→partner) and Y-score (partner→GSTP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	Negative regulation of monocyte chemotactic protein-1 production →	+1.020	+5.908	.001	<.001	3	12
BLOOD_Myeloma	Negative regulation of smooth muscle cell chemotaxis →	+0.828	+4.568	.009	<.001	3	12
BREAST	Negative regulation of acute inflammatory response →	+0.444	+5.962	<.001	<.001	3	12
KIDNEY	Glutathione derivative biosynthetic process →	+0.307	+5.874	.002	<.001	3	10
BLOOD_Lymphoma	Cellular response to cell-matrix adhesion →	+0.492	+3.344	.004	<.001	3	9
LIVER	Negative regulation of smooth muscle cell migration →	+0.166	+6.205	.002	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,444 associations by consensus.

Negative regulation of monocyte chemotactic protein-1 production by GSTP1 expression — BLOOD_Myeloma

Explore this box plot interactively →