GSTO3P

Across TCGA pan-cancer cohorts, GSTO3P RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of GSTO3P’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where GSTO3P RNA is more highly expressed in tumor relative to normal tissue. In most cancer types GSTO3P is over-expressed in tumor, although a few such as LUAD show the opposite, repressed pattern.

KIRC, PRAD, and LUAD are the cancer types where GSTO3P tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in GSTO3P RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	All	III,IV	+0.038	.005	5	view →
PRAD	All	All	+0.127	.001	2	view →
LUAD	Female	II,III,IV	−0.085	.005	2	view →
BRCA	Female	All	+0.050	.010	2	view →
HNSC	All	All	+0.036	.034	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

GSTO3P–KIRC

Open the KIRC breakdown →