GSTO1

Across TCGA patient cohorts, GSTO1 protein abundance is significantly associated with the RNA expression of many other genes, with 10,973 significant associations in total. GBM shows the largest number of these associations.

The most reproducible GSTO1-associated genes across cancer lineages are VSIG4, ITGAM, and SPI1. Each is linked with GSTO1 in more than 6 cancer types. Because this analysis shows association rather than direction, both GSTO1-to-partner and partner-to-GSTO1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GSTO1 versus VSIG4 in HNSC, with a Pearson correlation of 0.28.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GSTO1→partner) and Y-score (partner→GSTO1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	VSIG4 →	+1.164	+0.242	.006	.002	3	7
UCEC	ITGAM →	+0.817	+0.265	.001	.005	3	7
LUAD	SPI1 →	+0.721	+0.293	<.001	<.001	3	7
HNSC	MS4A4A →	+1.293	+0.281	<.001	<.001	3	6
GBM	SELPLG →	+0.762	+0.305	<.001	<.001	3	6
LSCC	CLIP4 →	+0.939	+0.425	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,973 associations by consensus.

GSTO1 vs VSIG4 — HNSC

Explore this scatter interactively →