GSTM3

Across TCGA patient cohorts, GSTM3 protein abundance is significantly associated with the RNA expression of many other genes, with 16,853 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible GSTM3-associated genes across cancer lineages are SYNGR1, GSTM4, and AMIGO1. Each is linked with GSTM3 in more than 5 cancer types. Because this analysis shows association rather than direction, both GSTM3-to-partner and partner-to-GSTM3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GSTM3 versus SYNGR1 in HNSC, with a Pearson correlation of 0.32.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GSTM3→partner) and Y-score (partner→GSTM3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	SYNGR1 →	+0.992	+0.850	<.001	.002	3	6
LSCC	GSTM4 →	+0.927	+1.385	<.001	<.001	3	6
BRCA	AMIGO1 →	+0.687	+1.161	<.001	<.001	3	6
OV	GABARAPL1 →	+0.650	+0.507	<.001	<.001	3	5
HNSC	EPHX1 →	+0.968	+1.021	<.001	<.001	3	5
LSCC	TSPAN7 →	+1.156	+1.031	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,853 associations by consensus.

GSTM3 vs SYNGR1 — HNSC

Explore this scatter interactively →