Across TCGA patient cohorts, GSTM2 protein abundance is significantly associated with the RNA expression of many other genes, with 13,769 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible GSTM2-associated genes across cancer lineages are FHL1, CBX7, and GSTM3. Each is linked with GSTM2 in more than 7 cancer types. Because this analysis shows association rather than direction, both GSTM2-to-partner and partner-to-GSTM2 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GSTM2→partner) and Y-score (partner→GSTM2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	FHL1 →	+1.529	+0.738	<.001	<.001	3	8
HNSC	CBX7 →	+0.846	+1.278	<.001	<.001	3	8
HNSC	GSTM3 →	+1.928	+1.188	<.001	<.001	3	7
HNSC	MYL3 →	+0.996	+0.576	<.001	<.001	3	7
HNSC	PI16 →	+1.473	+0.970	<.001	<.001	3	7
BRCA	MFAP4 →	+1.804	+0.594	<.001	.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,769 associations by consensus.

Exploration

GSTM2 survival (RNA) · tumor vs normal (RNA) · all GSTM2 data types