GSTM1

Across TCGA patient cohorts, GSTM1 RNA expression is significantly associated with the RNA expression of many other genes, with 5,149 significant associations in total. TGCT shows the largest number of these associations.

The most reproducible GSTM1-associated genes across cancer lineages are GSTM5, GSTM4, and GSTM2. Each is linked with GSTM1 in more than 27 cancer types. Because this analysis shows association rather than direction, both GSTM1-to-partner and partner-to-GSTM1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GSTM1 versus GSTM5 in TGCT, with a Pearson correlation of 0.35.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GSTM1→partner) and Y-score (partner→GSTM1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
TGCT	GSTM5 →	+1.248	+1.957	<.001	<.001	3	28
BLCA	GSTM4 →	+1.334	+2.664	<.001	<.001	3	26
BLCA	GSTM2 →	+1.363	+1.976	<.001	<.001	3	25
KICH	GSTM3 →	+2.762	+3.016	<.001	<.001	2	22
GBM	GSTM2P1 →	+0.549	+2.941	<.001	<.001	3	19
TGCT	MAOA →	+0.988	+1.496	<.001	.001	2	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,149 associations by consensus.

GSTM1 vs GSTM5 — TGCT

Explore this scatter interactively →