GSTM1

Across TCGA patient cohorts, GSTM1 protein abundance is significantly associated with the RNA expression of many other genes, with 2,074 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible GSTM1-associated genes across cancer lineages are GSTM4, GSTM2, and RPL31P20. Each is linked with GSTM1 in more than 2 cancer types. Because this analysis shows association rather than direction, both GSTM1-to-partner and partner-to-GSTM1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GSTM1 versus GSTM4 in COAD, with a Pearson correlation of 0.33.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GSTM1→partner) and Y-score (partner→GSTM1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	GSTM4 →	+0.467	+0.967	.002	.004	3	3
CCRCC	GSTM2 →	+0.464	+0.928	<.001	.001	3	3
UCEC	RPL31P20 →	-1.186	-0.930	.002	.004	3	2
HNSC	MIR148B →	+0.868	+1.074	.002	.008	3	2
BRCA	GSTM5 →	+0.767	+1.055	.003	.003	2	3
CCRCC	PDZK1P1 →	+0.341	+0.858	.003	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,074 associations by consensus.

GSTM1 vs GSTM4 — COAD

Explore this scatter interactively →