Across TCGA pan-cancer cohorts, GSTK1 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated GSTK1 data layer compared with 29 for mass-spec protein and 5 for mutation status.

The strongest signal is observed in glioblastoma multiforme (GBM), where higher GSTK1 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated GSTK1 expression acts as an unfavorable survival marker, although some lineages such as CCRCC show a favorable association.

GBM, LUAD, and CCRCC are the cancer types where GSTK1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
GBM	OS	Median	All	0.422	0.627	.003	22	view →
LUAD	DFS	Median	III,IV	0.409	0.941	.010	8	view →
CCRCC	OS	Tertile	II,III,IV	0.989	0.133	.020	6	view →
PDAC	OS	Quartile	II,III,IV	0.733	0.911	.039	1	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

Exploration

Same gene, other analysis: GSTK1 tumor-vs-normal RNA expression · all GSTK1 data types