Across TCGA patient cohorts, GSTK1 mutation is significantly associated with the total protein of many other genes, with 4 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GSTK1-associated genes across cancer lineages are Notch1, PCNA, and Beclin. Each is linked with GSTK1 in more than 1 cancer types. Because this analysis shows association rather than direction, both GSTK1-to-partner and partner-to-GSTK1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GSTK1→partner) and Y-score (partner→GSTK1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Notch1 →	+0.128	+2.335	.027	.018	3	1
UCEC	PCNA →	+0.187	+1.807	.036	.027	3	1
UCEC	Beclin →	+0.085	+3.000	.028	.001	3	1
UCEC	Caspase-7-cleavedD198 →	+0.903	+2.459	<.001	.018	3	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

Exploration

GSTK1 survival (RNA) · tumor vs normal (RNA) · all GSTK1 data types