Q-omics provides the consensus-scored GSTA8P profile across patient tissues and cancer cell-line models. GSTA8P expression is associated with patient survival in 13 of 34 cancer types, with the highest sampling consensus in CESC. Among the 18 cancer types available for tumor–normal comparison, GSTA8P is differentially expressed in 8, with the highest sampling consensus in KIRC. Additionally, GSTA8P RNA expression shows 8,097 significant protein co-abundance associations, with the highest sampling consensus in HNSC. Together, these results highlight CESC, KIRC, and HNSC as cancer lineages where GSTA8P shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for GSTA8P — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes GSTA8P survival associations across molecular data types. GSTA8P RNA expression shows survival associations in the most cancer types (13). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible GSTA8P RNA expression–survival associations across cancer types. High GSTA8P expression shows unfavorable associations in THCA, KICH and UCS, but favorable associations in CESC, LUSC and COAD. The CESC Kaplan–Meier curve shows clear separation, with the low-expression group declining faster, consistent with the favorable association (log-rank p = .001). Together, the overview and detailed table identify CESC as the clearest survival context for GSTA8P RNA expression.
This table summarizes GSTA8P tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 8. The strongest signals are observed in KIRC for RNA.
This table ranks reproducible tumor–normal expression differences for GSTA8P. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. GSTA8P shows lower tumor expression in THCA, KICH and ESCA and higher tumor expression in KIRC, LUSC and LIHC. The KIRC box plot shows higher GSTA8P RNA expression in tumor versus normal tissue (log2 FC = +0.120, t-test p < 0.001).
This table shows molecular features associated with GSTA8P in patient tissues and cancer cell lines. In patient samples, GSTA8P shows the broadest associations at the RNA and protein expression levels, with HNSC recurring as the lineage with the largest associated feature set.
