GSS

Across TCGA patient cohorts, GSS RNA expression is significantly associated with the protein abundance of many other proteins, with 15,420 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible GSS-associated proteins across cancer lineages are PIGU, TOMM34, and HSPA14. Each is linked with GSS in more than 4 cancer types. Because this analysis shows association rather than direction, both GSS-to-partner and partner-to-GSS results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GSS versus PIGU in BRCA, with a Pearson correlation of 0.33.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GSS→partner) and Y-score (partner→GSS) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	PIGU →	+0.474	+0.468	.001	.001	3	5
COAD	TOMM34 →	+0.463	+0.424	<.001	<.001	3	5
LSCC	HSPA14 →	+0.387	+0.522	<.001	<.001	3	5
LSCC	SH3BGRL →	-0.391	-0.474	<.001	<.001	3	5
LSCC	MDM1_T515 →	-0.485	-0.456	<.001	<.001	3	5
CCRCC	UQCC2 →	+0.433	+0.354	<.001	.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,420 associations by consensus.

GSS vs PIGU — BRCA

Explore this scatter interactively →