GSR

Across TCGA patient cohorts, GSR RNA expression is significantly associated with the protein abundance of many other proteins, with 16,266 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible GSR-associated proteins across cancer lineages are XPO7, PCM1, and SARAF. Each is linked with GSR in more than 6 cancer types. Because this analysis shows association rather than direction, both GSR-to-partner and partner-to-GSR results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GSR versus XPO7 in OV, with a Pearson correlation of 0.37.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GSR→partner) and Y-score (partner→GSR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	XPO7 →	+0.275	+0.673	.002	.001	3	7
OV	PCM1 →	+0.439	+0.792	<.001	<.001	3	7
BRCA	SARAF →	+0.456	+0.704	.005	<.001	3	7
UCEC	PBK →	+0.635	+0.829	<.001	.001	3	6
BRCA	PPP2CB →	+0.533	+0.854	<.001	<.001	3	6
BRCA	SH2D4A →	+0.443	+0.708	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,266 associations by consensus.

GSR vs XPO7 — OV

Explore this scatter interactively →