GSKIP

Across TCGA pan-cancer cohorts, GSKIP mass-spec protein is linked to patient survival in 7 of 34 cancer types, making it a survival-associated GSKIP data layer compared with 26 for mass-spec protein and 2 for mutation status.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher GSKIP mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated GSKIP expression acts as an unfavorable survival marker, although some lineages such as UCEC and HNSC show a favorable association.

UCEC, CCRCC, and HNSC are the cancer types where GSKIP mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	DFS	Median	III,IV	1.000	0.274	.001	62	view →
CCRCC	OS	Median	All	0.793	0.990	<.001	49	view →
HNSC	DFS	Median	All	0.895	0.398	.014	24	view →
PDAC	OS	Median	IV	0.381	0.951	.006	10	view →
OV	DFS	Tertile	All	0.536	1.000	.017	8	view →
LUAD	OS	Median	II,III,IV	0.449	0.893	.023	3	view →
LSCC	DFS	Median	All	0.568	0.936	.045	2	view →

Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

GSKIP–UCEC (DFS)

Open the UCEC breakdown →