GSKIP

Across TCGA patient cohorts, GSKIP protein abundance is significantly associated with the RNA expression of many other genes, with 10,858 significant associations in total. COAD shows the largest number of these associations.

The most reproducible GSKIP-associated genes across cancer lineages are SETD3, PRKN, and CINP. Each is linked with GSKIP in more than 4 cancer types. Because this analysis shows association rather than direction, both GSKIP-to-partner and partner-to-GSKIP results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GSKIP versus SETD3 in BRCA, with a Pearson correlation of 0.34.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GSKIP→partner) and Y-score (partner→GSKIP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	SETD3 →	+0.467	+0.301	<.001	.002	3	5
LSCC	PRKN →	-0.479	-0.345	<.001	<.001	3	4
LSCC	CINP →	+0.405	+0.270	<.001	<.001	3	4
HNSC	RAB9B →	-0.552	-0.287	<.001	<.001	3	4
HNSC	ANKRD23 →	-0.534	-0.305	<.001	.002	3	4
HNSC	LDLRAD4 →	-0.874	-0.321	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,858 associations by consensus.

GSKIP vs SETD3 — BRCA

Explore this scatter interactively →