GSKIP

Across TCGA cell cohorts, GSKIP RNA expression is significantly associated with the go_rna of many other GO terms, with 3,832 significant associations in total. BONE shows the largest number of these associations.

The most reproducible GSKIP-associated GO terms across cancer lineages are Vesicle tethering, Membrane fission, and Protein catabolic process at synapse. Each is linked with GSKIP in more than 11 cancer types. Because this analysis shows association rather than direction, both GSKIP-to-partner and partner-to-GSKIP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Vesicle tethering grouped by GSKIP-low versus GSKIP-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GSKIP→partner) and Y-score (partner→GSKIP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Vesicle tethering →	+0.106	+0.968	<.001	<.001	3	12
BLOOD_Leukemia	Membrane fission →	+0.066	+0.689	<.001	.002	3	12
BLOOD_Lymphoma	Protein catabolic process at synapse →	+0.138	+0.781	<.001	<.001	3	11
BLOOD_Lymphoma	Protein catabolic process at postsynapse →	+0.138	+0.781	<.001	<.001	3	11
URINARY_TRACT	Monoubiquitinated protein deubiquitination →	+0.131	+1.298	<.001	<.001	3	11
BLOOD_Lymphoma	Golgi vesicle transport →	+0.054	+1.022	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,832 associations by consensus.

Vesicle tethering by GSKIP expression — LUNG_SCLC

Explore this box plot interactively →