GSKIP

Across TCGA cell cohorts, GSKIP mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible GSKIP-associated genes across cancer lineages are OR4K1 and TGM7. Each is linked with GSKIP in more than 1 cancer types. Because this analysis shows association rather than direction, both GSKIP-to-partner and partner-to-GSKIP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR4K1 grouped by GSKIP-low versus GSKIP-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GSKIP→partner) and Y-score (partner→GSKIP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	OR4K1 →	+0.019	+5.228	<.001	.005	3	1
LUNG_NSCLC_LUAD	TGM7 →	+0.006	+4.887	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

OR4K1 by GSKIP expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →