GSK3B

Across TCGA patient cohorts, GSK3B RNA expression is significantly associated with the protein abundance of many other proteins, with 15,857 significant associations in total. GBM shows the largest number of these associations.

The most reproducible GSK3B-associated proteins across cancer lineages are FXR1, XPO1, and ZNF148. Each is linked with GSK3B in more than 4 cancer types. Because this analysis shows association rather than direction, both GSK3B-to-partner and partner-to-GSK3B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GSK3B versus FXR1 in LUAD, with a Pearson correlation of 0.45.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GSK3B→partner) and Y-score (partner→GSK3B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	FXR1 →	+0.298	+0.308	<.001	.004	3	5
LSCC	XPO1 →	+0.306	+0.681	<.001	<.001	3	5
HNSC	ZNF148 →	+0.326	+0.727	<.001	<.001	3	4
LSCC	SAE1 →	+0.332	+0.662	<.001	<.001	3	4
LSCC	CPOX →	+0.380	+0.435	<.001	<.001	3	4
GBM	CSTF3 →	+0.252	+0.436	.003	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,857 associations by consensus.

GSK3B vs FXR1 — LUAD

Explore this scatter interactively →