GSK3A

Across TCGA cell cohorts, GSK3A RNA expression is significantly associated with the go_rna of many other GO terms, with 3,590 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible GSK3A-associated GO terms across cancer lineages are Regulation of protein localization to centrosome, Negative regulation of calcium ion export across plasma membrane, and Regulation of base-excision repair. Each is linked with GSK3A in more than 12 cancer types. Because this analysis shows association rather than direction, both GSK3A-to-partner and partner-to-GSK3A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of protein localization to centrosome grouped by GSK3A-low versus GSK3A-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GSK3A→partner) and Y-score (partner→GSK3A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Regulation of protein localization to centrosome →	+0.100	+0.853	.001	.004	3	13
STOMACH	Negative regulation of calcium ion export across plasma membrane →	+0.072	+0.877	.009	.005	3	13
STOMACH	Regulation of base-excision repair →	+0.128	+0.745	.004	.001	3	12
STOMACH	Nucleosome organization →	+0.094	+0.986	<.001	<.001	3	12
BLOOD_Myeloma	Regulation of chromatin organization →	+0.085	+0.821	<.001	<.001	3	12
BONE	Constitutive heterochromatin formation →	+0.109	+0.663	.005	.005	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,590 associations by consensus.

Regulation of protein localization to centrosome by GSK3A expression — STOMACH

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