Across TCGA pan-cancer cohorts, GSG1L2 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of GSG1L2’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where GSG1L2 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types GSG1L2 is over-expressed in tumor.

KIRC and LUSC are the cancer types where GSG1L2 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in GSG1L2 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Male	All	+1.625	<.001	8	view →
LUSC	All	All	+0.008	.049	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 2 strongest of 2 lineages.

Exploration

Same gene, other analysis: GSG1L2 RNA expression & survival · all GSG1L2 data types