GSG1

Across TCGA cell cohorts, GSG1 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,137 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible GSG1-associated GO terms across cancer lineages are Bleb assembly, Positive regulation of transcription by RNA polymerase III, and Fibrinolysis. Each is linked with GSG1 in more than 5 cancer types. Because this analysis shows association rather than direction, both GSG1-to-partner and partner-to-GSG1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Bleb assembly grouped by GSG1-low versus GSG1-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GSG1→partner) and Y-score (partner→GSG1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Bleb assembly →	+0.240	+0.626	<.001	.007	3	5
BLOOD_Myeloma	Positive regulation of transcription by RNA polymerase III →	+0.064	+0.024	.005	.006	2	6
BLOOD_Leukemia	Fibrinolysis →	+0.635	+0.398	.001	.002	3	5
LUNG_SCLC	Interleukin-3-mediated signaling pathway →	-1.669	-0.483	<.001	.008	3	5
SKIN	Regulation of cardiac muscle adaptation →	+0.223	+0.070	<.001	<.001	3	5
SKIN	Negative regulation of cardiac muscle adaptation →	+0.242	+0.083	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,137 associations by consensus.

Bleb assembly by GSG1 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →