GSE1

Across TCGA cell cohorts, GSE1 mutation is significantly associated with the RNA expression of many other genes, with 841 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible GSE1-associated genes across cancer lineages are UBR7, ENOPH1, and GAGE12E. Each is linked with GSE1 in more than 2 cancer types. Because this analysis shows association rather than direction, both GSE1-to-partner and partner-to-GSE1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, UBR7 grouped by GSE1-low versus GSE1-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GSE1→partner) and Y-score (partner→GSE1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	UBR7 →	+0.644	+3.608	<.001	.001	3	3
BLOOD_Leukemia	ENOPH1 →	+0.395	+3.489	.008	.001	3	3
LUNG_NSCLC_LUSC	GAGE12E →	+0.076	+4.643	<.001	.008	3	2
OESOPHAGUS	HPGDS →	+0.072	+3.392	.002	.007	3	2
PANCREAS	LCE2A →	+0.033	+5.614	<.001	.002	3	2
LARGE_INTESTINE	CBY1 →	+0.767	+3.036	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 841 associations by consensus.

UBR7 by GSE1 expression — BLOOD_Leukemia

Explore this box plot interactively →