GSDMC

Across TCGA patient cohorts, GSDMC RNA expression is significantly associated with the protein abundance of many other proteins, with 17,483 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible GSDMC-associated proteins across cancer lineages are MYEF2, ERO1A, and VEZF1. Each is linked with GSDMC in more than 6 cancer types. Because this analysis shows association rather than direction, both GSDMC-to-partner and partner-to-GSDMC results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GSDMC versus MYEF2 in HNSC, with a Pearson correlation of -0.51.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GSDMC→partner) and Y-score (partner→GSDMC) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	MYEF2 →	-0.754	-1.251	<.001	<.001	3	7
BRCA	ERO1A →	+0.614	+1.347	<.001	<.001	3	7
BRCA	VEZF1 →	-0.428	-1.427	<.001	<.001	3	6
UCEC	KRT16 →	+1.762	+1.066	<.001	<.001	3	6
HNSC	ZNF185 →	+1.031	+2.279	<.001	<.001	3	6
CCRCC	CDCP1 →	+0.892	+0.480	<.001	.003	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,483 associations by consensus.

GSDMC vs MYEF2 — HNSC

Explore this scatter interactively →